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S 14506 hydrochloride

CAS No. 286369-38-8

S 14506 hydrochloride( —— )

Catalog No. M27699 CAS No. 286369-38-8

S 14506 hydrochloride is a 5-HT1A receptor full agonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    S 14506 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    S 14506 hydrochloride is a 5-HT1A receptor full agonist.
  • Description
    S 14506 hydrochloride is a 5-HT1A receptor full agonist.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male swiss albino mice (25-30 g) and male Wistar rats (170-230 g) Dosage:0.2 mg/kg, 0.8 mg/kg, 3.2 mg/kg, 3.8 mg/kg Administration:IP; single dose, 30 min before test Result:Inhibited stereotyped climbing and sniffing behaviours induced by dopamine agonists in mice and on spontaneous behaviours.Animal Model:Male Wistar rats (200-220 g)Dosage:0.01 mg/kg, 0.63 mg/kg Administration:SC; and gave antagonist 30 min after agonist Result:Induced a dose-dependent imobility in rats.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    ACAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    286369-38-8
  • Formula Weight
    443.94
  • Molecular Formula
    C24H26FN3O2·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (563.14 mM)
  • SMILES
    COC1=CC2=C(C=C1)C=CC=C2N3CCN(CC3)CCNC(C4=CC=C(F)C=C4)=O.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kashiwa M, et al. Pharmacological properties of YM17E, an acyl-CoA:cholesterol acyltransferase inhibitor, and diarrheal effect in beagle dogs. Jpn J Pharmacol. 1997 Jan;73(1):41-50.
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